Masamitsu Shimazawa Selected Research

Cognitive Dysfunction

1/2022	The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment.
1/2015	Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Masamitsu Shimazawa Research Topics

Disease

30	Ganglion Cysts (Ganglion) 01/2023 - 07/2004
22	Ischemia 01/2022 - 01/2008
20	Brain Ischemia (Cerebral Ischemia) 01/2023 - 01/2005
18	Glaucoma 02/2024 - 01/2004
16	Macular Degeneration (Age-Related Maculopathy) 01/2024 - 02/2011
15	Retinal Diseases 01/2022 - 01/2004
14	Retinal Vein Occlusion 01/2024 - 01/2017
14	Choroidal Neovascularization 01/2024 - 09/2014
14	Retinal Degeneration 10/2021 - 12/2010
14	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 11/2019 - 01/2005
13	Papilledema 01/2023 - 06/2017
13	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 08/2006
13	Retinal Neovascularization 01/2021 - 03/2007
13	Infarction (Infarctions) 01/2020 - 02/2008
12	Neoplasms (Cancer) 04/2024 - 11/2009
11	Brain Injuries (Brain Injury) 02/2022 - 08/2008
10	Stroke (Strokes) 01/2020 - 08/2008
9	Reperfusion Injury 10/2023 - 10/2009
9	Ischemic Stroke 01/2023 - 01/2011
8	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 12/2016
8	Neuroblastoma 01/2023 - 10/2006
8	Inflammation (Inflammations) 07/2021 - 08/2013
7	Edema (Dropsy) 01/2024 - 01/2017
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 10/2009
7	Hypoxia (Hypoxemia) 01/2022 - 08/2006
7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 10/2011
6	Atrophy 01/2021 - 12/2010
6	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 12/2020 - 02/2016
6	Intracranial Hemorrhages (Intracranial Hemorrhage) 11/2020 - 05/2016
6	Retinal Perforations 01/2017 - 08/2006
6	Melanoma (Melanoma, Malignant) 01/2017 - 01/2012
5	Hemorrhage 06/2024 - 02/2015
5	Macular Edema 01/2022 - 08/2006
5	Hematoma 01/2021 - 01/2017
5	Cerebral Infarction 07/2011 - 06/2007
5	Hyperoxia 05/2011 - 01/2008
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 01/2020
4	Ocular Hypertension (Glaucoma, Suspect) 01/2022 - 07/2004
4	Fibrosis (Cirrhosis) 01/2022 - 07/2018
4	Alzheimer Disease (Alzheimer's Disease) 02/2021 - 10/2009
4	Eye Diseases (Eye Disease) 01/2021 - 10/2010
4	Brain Edema (Cerebral Edema) 01/2020 - 12/2010
4	Blindness (Hysterical Blindness) 01/2018 - 02/2011
4	Pathologic Neovascularization 01/2017 - 08/2009
3	Hemorrhagic Stroke 01/2021 - 01/2017
3	Cerebral Hemorrhage 11/2018 - 01/2017
3	Constipation 10/2012 - 01/2010
3	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2012 - 08/2009
2	Myocardial Ischemia (Ischemic Heart Diseases) 10/2023 - 01/2020
2	Myocardial Infarction 10/2023 - 01/2020

Drug/Important Bio-Agent (IBA)

51	Retinaldehyde (Retinal)IBA 01/2024 - 01/2004
23	Neuroprotective AgentsIBA 01/2022 - 05/2005
22	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 08/2009
16	Proteins (Proteins, Gene)FDA Link 01/2023 - 10/2006
16	Oxygen (Dioxygen)IBA 01/2023 - 01/2007
13	N-Methylaspartate (NMDA)IBA 08/2013 - 08/2005
11	ProgranulinsIBA 11/2023 - 08/2013
10	TunicamycinIBA 01/2015 - 10/2006
8	AntioxidantsIBA 12/2021 - 01/2010
8	Cilostazol (Pletal)FDA LinkGeneric 01/2017 - 03/2009
7	Free Radical ScavengersIBA 01/2021 - 05/2009
7	EdaravoneIBA 11/2017 - 08/2008
6	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2007
6	astaxanthine (astaxanthin)IBA 09/2020 - 10/2008
6	IgA receptor (protein B)IBA 01/2017 - 01/2012
6	Glycoproteins (Glycoprotein)IBA 01/2017 - 01/2012
5	IronIBA 06/2024 - 12/2014
5	Indicators and Reagents (Reagents)IBA 04/2015 - 12/2006
5	Propolis (Bee Bread)IBA 10/2012 - 01/2005
4	Hemoglobins (Hemoglobin)IBA 06/2024 - 10/2013
4	Collagenases (Collagenase)FDA Link 01/2021 - 01/2017
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2009
4	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 10/2013 - 12/2010
4	LaxativesIBA 10/2012 - 02/2008
4	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 12/2011 - 01/2009
3	OccludinIBA 01/2023 - 02/2013
3	Peptides (Polypeptides)IBA 01/2023 - 05/2011
3	Temozolomide (Temodar)FDA LinkGeneric 11/2022 - 11/2019
3	4- (4- acetylpiperazin- 1- yl)- 2- (1H- imidazol- 1- yl)anilineIBA 01/2021 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 11/2019 - 01/2012
3	Tight Junction ProteinsIBA 01/2019 - 02/2013
3	trans-sodium crocetinate (crocetin)IBA 01/2019 - 01/2011
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2018 - 08/2013
3	Protein Isoforms (Isoforms)IBA 01/2018 - 12/2012
3	Kallikreins (Kallikrein)IBA 06/2017 - 09/2014
3	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2017 - 03/2009
3	Warfarin (Coumadin)FDA LinkGeneric 01/2017 - 10/2013
3	Sigma-1 ReceptorIBA 03/2015 - 05/2013
3	LigandsIBA 11/2013 - 09/2005
3	Glutamic Acid (Glutamate)FDA Link 06/2012 - 05/2005
3	ZincIBA 12/2009 - 01/2008
2	Hemin (Panhematin)FDA Link 06/2024 - 01/2020
2	RotenoneIBA 01/2024 - 10/2021
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2023 - 10/2009

Therapy/Procedure

24	Lasers (Laser) 02/2024 - 07/2004
19	Therapeutics 01/2022 - 08/2008
10	Oral Administration 04/2024 - 08/2012
5	Light Coagulation 01/2017 - 07/2004
4	Intravitreal Injections 01/2021 - 08/2005
4	Ligation 11/2016 - 12/2011